منابع مشابه
Prediction of quaternary structure from primary structure
MOTIVATION The 'sequence implies conformation' principle has been the motivation for the construction of numerous systems of secondary and tertiary structure prediction. Computational experiments have shown that this principle can now be extended to quaternary structure prediction. This work appears to be the first effort to predict quaternary structure properties from sequence. RESULTS The s...
متن کاملRegulation of Uridine Kinase Quaternary Structure
Uridine kinase from mouse Ehrlich ascites cells can exist in a variety of different aggregation states, from monomer up to aggregates that may contain 32 or more subunits. With very crude enzyme preparations, uridine kinase activity is always associated with several different coexisting molecular weight species. Changes in the aggregation state are produced in the presence of normal effectors (...
متن کاملThe structure of quaternary quantum caps
We give a geometric description of binary quantum stabilizer codes. In the case of distance d = 4 this leads to the notion of a quaternary quantum cap. We describe several recursive constructions for quantum caps, determine the quantum caps in PG(3, 4) and the cardinalities of quantum caps in PG(4, 4). ∗research partially supported NSA grant H98230-10-1-0159 †The research of this author takes p...
متن کاملQuaternary structure of hemoglobin in solution.
Many important proteins perform their physiological functions under allosteric control, whereby the binding of a ligand at a specific site influences the binding affinity at a different site. Allosteric regulation usually involves a switch in protein conformation upon ligand binding. The energies of the corresponding structures are comparable, and, therefore, the possibility that a structure de...
متن کاملThe Quaternary Structure of Yeast Aminopeptidase I
The smallest active form of aminopeptidase I (EC 3.4.11.1) from yeast has a molecular weight of 6.4 X 105. At neutral pH the active enzyme is in equilibrium with two inactive subfragments (Mr = 3 .2X 105 and 1.1 X 105) as well as with higher aggregates (Mr 1.2 X 106). All of these species may be dissociated to give a single type of subunits with a molecular weight of 5.3 X 104. It is concluded ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1975
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.72.3.1043